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Systane Ultra is Safe for Use with Contact Lenses

Systane Ultra is safe for use while wearing with contact lenses according to a new study.

Clinical Evaluation of Systane Ultra Safety in Contact Lens Wearers

This investigator- and patient-masked, single-site, randomized, and prospective study involved 45 successful contact lens wearers to evaluate the safety of Systane Ultra Lubricant Eye Drops in contact lens wearers. A currently marketed contact lens rewetting drop was the control solution. Eligible subjects’ baseline biomicroscopy findings, visual acuity, and corneal staining score were recorded. Subjects received either the test or control solution with masked labeling. Subjects were instructed to instill their assigned solution in both eyes: 15 minutes prior to lens insertion, at least one drop during lens wear and another drop immediately following lens removal. After 14 days, biomicroscopy results, visual acuity, and corneal staining score were recorded.

No adverse events were documented for either the test or the control solution. For subjects using Systane Ultra, no statistically significant change was detected in visual acuity or corneal staining score. For subjects using the control solution, the change in visual acuity was not clinically relevant and there was no significant change in corneal staining score.

This clinical study provided evidence of safety and compatibility of Systane Ultra Lubricant Eye Drops in contact lens wearers.

SOURCE: Kading D. A two-week clinical evaluation of the safety of Systane Ultra in contact lens-wearing patients. Clin Ophthalmol 2010;4:27-32.

I have actually wanted to find out whether it binds to and gums up the contact lens. Or is this condition considered part of the “no adverse events.” Also, does it matter whether the contact is a two week lens verses a one month lens?

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  1. Nick says

    I regularly use both Systane Ultra and Systane Balance while wearing contact lenses, it works just fine with no side effects.

Written by David Langford, O.D.

David Langford is a graduate of PUCO 2003, worked as a USPHS/IHS optometrist, then as fill-in commercial, then solo private practice, and now works full time as an independent doctor of optometry inside a Wal-Mart Vision Center.

David Langford, O.D. has written 426 posts on

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